Lifestyle Environment and Cancer Genes

Lifestyle habits and environmental factors can alter gene expression, thereby affecting the occurrence and recurrence of cancer.

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This article, written from the perspective of patients in Hong Kong, explains how diet, exercise, stress management, and nutritional supplements affect epigenetics, helping cancer patients boost their immunity and reduce the risk of recurrence.

The Relationship Between Lifestyle Environment and Cancer Genes

Research shows that only about 5–10% of cancers are caused by inherited genes, while more than 85% are linked to lifestyle and environmental factors. Dietary habits, lack of exercise, obesity, environmental toxins, stress, and poor sleep can all influence epigenetic switches—turning cancer-promoting or cancer-suppressing genes on or off.

Changing Lifestyle, Changing Gene Expression

Cancer is closely related to epigenetic changes. The good news is that lifestyle adjustments can guide gene expression in a healthier direction.

1. Anti-Inflammatory Diet

The Mediterranean diet has been widely proven to lower cancer risk. Eating a variety of vegetables, fruits, fish, nuts, olive oil, whole grains, and legumes—while reducing refined carbohydrates and sugars—helps lower insulin and IGF-1 secretion, depriving tumors of excess nutrients.

2. Exercise

Moderate aerobic activity for 30 minutes a day, at least five days a week, combined with resistance training, can reduce inflammatory hormones, lower harmful hormone levels, and strengthen natural killer (NK) cells and T-cell function to suppress cancer growth.

3. Stress Reduction and Psychological Support

Chronic stress, anxiety, and social isolation raise stress hormones, weaken immunity, and accelerate cancer progression. Practices like yoga, meditation, mindfulness, music therapy, and cancer support groups can reduce inflammatory markers and improve gene expression.

4. Anti-Inflammatory Nutrients

Scientific studies suggest curcumin, vitamin D3, fish oil, and vitamin C may support epigenetic regulation. However, supplements must be used under medical guidance to avoid interactions with ongoing treatments.

5. Enhancing Immune Function

Beneficial immune cells such as NK cells and CD8 T lymphocytes attack cancer cells directly. A combination of diet, exercise, stress management, and probiotics can optimize immune balance and strengthen anti-cancer defense.

Conclusion

Cancer is not solely a genetic issue—it is strongly influenced by lifestyle choices. Through balanced nutrition, regular physical activity, stress management, and evidence-based supplementation, patients can positively influence epigenetic expression, improve quality of life, and reduce recurrence risk.

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References

  • American Cancer Society. (2023). Lifestyle changes and cancer prevention. Retrieved from https://www.cancer.org
  • World Health Organization. (2022). Cancer prevention. Retrieved from https://www.who.int
  • National Cancer Institute. (2023). Epigenetics and cancer. Retrieved from https://www.cancer.gov
  • Antoni, M. H., Lutgendorf, S. K., & Cole, S. W. (2016). Biobehavioral influences on cancer progression and survival. Nature Reviews Cancer, 16(6), 361–375.
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