NK Cells and Cancer: A Patient-Centered Exploration of Natural Killer Immunity and Its Future in Cancer Care
Cancer remains one of the top global killers, and while many patients focus on surgery, chemotherapy, or targeted drugs, an equally decisive factor is the body’s own immune defense. Natural killer (NK) cells are a key component of innate immunity, capable of detecting and destroying abnormal or malignant cells without requiring prior activation. Unlike T cells, NK cells do not depend on antigen presentation but instead carry out spontaneous surveillance and cytotoxicity through perforin and granzyme pathways. This unique ability positions NK cells as a critical barrier against cancer initiation and early tumor growth.

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